Clinical Application of Microporous Catheter Technology

Porous Catheter technology has the potential to allow clinical application of bioengineering principles to provide direct interstitial therapy.

The Twin Star Catheter may be configured to treat a range of clinical conditions, including:

      Soft Tissue Interstitial Drainage
        • Extremity Compartment Syndrome
        • Brain Injury
        • Reconstructive Flaps
        • Burns
        • Surgical incisions

      Drug Delivery
        • Chemotherapeutics
        • Antibiotics
        • Pain medications
        • Regenerative growth factors

In these catheters, the pore size can be much smaller than soft tissue cells. This small pore size enhances tissue microcirculation by accessing interstitial spaces between cells for local or site–specific tissue drainage and infusion.

The material and pore size determine what can or cannot pass through the wall of the tubules. The selection of porous material is based primarily on the size of molecules to be removed or retained, as well as other physical properties.

Positioning microporous catheters in tissues has been used previously for assay, using diffusion gradients (microdialysis) and hydrostatic gradients (capillary ultrafiltration probes). There is no therapeutic intention in those applications.

   
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